Gentamicin Injection

Category: Antibiotics and Anti Inefectives

Composition :	20mg/2ml, 40mg/1ml, 80mg/2ml, 400mg/10ml,1200mg/30ml
Gentamicin:	Potent antibiotic having a broader spectrum of action against a wide variety of bacterial infections.
Indications :	Valuable in critically ill patients, with impaired host defence, burns, urinary tract infections, lung abscesses, osteomyelitis, middle ear infection, septicaemia, meningitis caused by gram negative bacilli.
Dosage :	3-5 mg/kg body wt IM or IV daily in 3 divided doses for 7 to 10 days, 25-50 mg/kg/day
Contra-Indications:	25-50 mg/kg/day.
Contra-indications :-	Uraemia, severe renal function impairment; pregnancy, neonatals (except in life threatening situations)
Special Precautions:	Dose of gentamicin must be precisely calculated according to body wt and level of renal function.
Paediatrics :	Reduced dose necessary.

Vancomycin Injection

Vancomycin is an antibiotic used to treat certain heart, bone, joint, lung (respiratory tract), skin, blood, or urinary tract infections. Vancomycin injection can prevent heart infection (endocarditis) in penicillin-allergic patients who are having dental work or surgery.

Composition :	500mg & 1gm
Indications :	Antibiotic for Pseudomembranous Enterocolitis, meningitis.
Contraindications :	Hypersensitivity.
Adverse Effects :	Fever, rashes, redness, hushing etc.
Drug Interactions :	Additive action with other nephrotoxic drugs
Dosage :	Adult : 250-500 mg after 6 hr, Children : 40mg/kg in 4 divided doses, Neonates: 15mg/kg.

Piperacillin & Tazobactam Injection

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using Rozucor (GENERIC FOR CRESTOR).

Uses:     
This medication is used to treat a wide variety of bacterial infections. This medication is a combination of 2 drugs. Piperacillin is a penicillin-type antibiotic that works by stopping the growth of bacteria. Tazobactam is an enzyme inhibitor (beta-lactamase inhibitor) that helps the piperacillin work better.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). 

Meropenem Injection

Meropenem is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic. It works by stopping the growth of bacteria. This antibiotic treats onlybacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

How to use:     
This medication is given by injection into a vein, usually every 8 hours or as directed by your doctor.
Follow all instructions for proper mixing with the correct IV fluids. Consult your doctor for details. Before using, check the product visually for particles or discoloration. If either is present, do not use the liquid.
Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. The dosage is based on your medical condition and response to treatment.

Cefepime Injection

It is a semi synthetic, broad spectrum, fourth generation cephalosporin. It exerts its effects by inhibiting the peptidoglycan synthesis in microbial cell wall.

Composition :	250mg,500mg,1gm,2 gm
Indications :	Moderate to severe pneumonia, septicaemia, UTI, skin & skin structure infections, intra-abdominal infections.
Contraindications :	Impaired hepatic function. Impaired hypertension, hypersensitivity.
Safety Profile :	Pregnancy, lactation, pediatric dose adjustment required.
Drug Interactions :	Aminoglycoside & other antibiotic may increase the nephrotoxicity & ototoxicity.
Dosage :	Febrile neutropenia thrice a day 1-2 gm IV, other 1-2 gm IV.

Ceftazidime Injection

Category: Antibiotics and Antiinfectives

Composition :	250mg,500mg,1gm
Ceftazidime :	It is a broad spectrum, third generation parenteral cephalosporin effective against many Gram negative organisms.
Indication :	Serious infections of the respiratory tract, E.N.T, skin and soft tissue bone, and joints, biliary and G.I tract. U.T.I. Septicaemia, meningitis.infections in immuno compromised patients
Dosage :
Adults :	1-6 gm daily in divided doses every 8 or 12 hrs
Children (Over 1yr):	30-100 mg/kg body wt per day in 2-3 divided doses. Max 6 gm daily.
Contra-Indications :	Hypersensitivity to penicillins or Cephalosporins
Special Precautions :	Neonates and infants, renal of hepatic impairment, prolong use.

Cefuroxime Injection

Category: Antibiotics and Anti- Infectives

Composition :	100mg/2ml, 250 mg/2ml & 500mg/2ml
Amikacin:	It is semisynthetic aminoglycoside virtually identical to its parent compound kanamycin. Amikacin is effective against a variety of aerobic gram-negative bacilli including those that are resistant to gentamicin and other Aminoglycosides (Escherichia Coli, Pseudomonas Aeruginosa, Indole positive and negative Proteus species Klebsiella, Enterobacter, Serratia, Acinetobacter, Citobacter Freundii and providencia stuarti). It is effective against both penicillinase and non-penicillinase producing Staphylococcus Aureus. Amikacin shows excellent activity against Mycobacterium Tuberculosis and Atypical Mycobacteria.
Indications :	Bacteraemias, septicaemias, respiratory tract, bone and joints, CNS (including meningitis), soft tissue, intra-abdominal infections (including peritonitis), burns and post-operative infections.
Dosage :	IM route for Adults, Children: 15 mg/kg body weight/day in 2 or 3 divided doses. Max of 1.5 gm/day. Neonatals: 10 mg/kg body weight followed by 7.5 mg/kg every 12 hours IV route dosage is identical, injection spread over 2-3 mins or a slow IV infusion spread over a period of 30-60 mins and for infants and neonatals 1-2 hours.
Contra-Indications:	Known hypersensitive to aminoglycoside.
Special Precautions:	Impaired renal function, ensure adequate hydration.

Amikacin Injection

Category: Antibiotics and Anti- Infectives

Composition :	100mg/2ml, 250 mg/2ml & 500mg/2ml
Amikacin:	It is semisynthetic aminoglycoside virtually identical to its parent compound kanamycin. Amikacin is effective against a variety of aerobic gram-negative bacilli including those that are resistant to gentamicin and other Aminoglycosides (Escherichia Coli, Pseudomonas Aeruginosa, Indole positive and negative Proteus species Klebsiella, Enterobacter, Serratia, Acinetobacter, Citobacter Freundii and providencia stuarti). It is effective against both penicillinase and non-penicillinase producing Staphylococcus Aureus. Amikacin shows excellent activity against Mycobacterium Tuberculosis and Atypical Mycobacteria.
Indications :	Bacteraemias, septicaemias, respiratory tract, bone and joints, CNS (including meningitis), soft tissue, intra-abdominal infections (including peritonitis), burns and post-operative infections.
Dosage :	IM route for Adults, Children: 15 mg/kg body weight/day in 2 or 3 divided doses. Max of 1.5 gm/day. Neonatals: 10 mg/kg body weight followed by 7.5 mg/kg every 12 hours IV route dosage is identical, injection spread over 2-3 mins or a slow IV infusion spread over a period of 30-60 mins and for infants and neonatals 1-2 hours.
Contra-Indications:	Known hypersensitive to aminoglycoside.
Special Precautions:	Impaired renal function, ensure adequate hydration.

Acyclovir Injection

Category: Antiviral

Acyclovir : It is deoxiguanosine analog and requires a virus specific enzyme for conversion to the active metabolite that inhibits DNA synthesis and viral replication.

Composition :	250mg & 500mg
Indication :	Genital Herpes Simplex, Mucocutaneous H Simplex Encephalitis, H Simplex Keratitis, Herpes Zoster, Chicken Pox etc.
Dosage :	Adults: Herpes Simplex: 200 mg 5 times daily at 4 hrs interval for 5 days Herpes Zoster: 800 mg 5 times daily 4 hrs interval for 7 days Prophylaxis in Suppression: 200 mg 4 times daily
Children :	(Abpve 2 yrs) Dose same as adult.
Children :	(Below 2 yrs) Herpes Simplex: 100 mg 5 times at 4 hrs interval Prophylaxis: 100 mg 4 times daily at 6 hrs interval.
Contra-Indications :	Hypersensitivity, glaucoma, psychiatric diseases, depression etc.
Special Precautions :	Renal impairment necessitates dose reduction. Maintain adequate hydration

Aztreonam Injection

Aztreonam is used to treat a wide variety of bacterial infections. This medication is an antibiotic that works by stopping the growth of bacteria. This antibiotic, antibiotic injections treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu).

How To Use:     
Inject this medication into a vein (intravenous-IV) or into a muscle (intramuscular-IM) as directed by your doctor. The dosage is based on your medical condition and response to therapy.

Follow all instructions for proper mixing and dilution with the correct IV fluids. If you are using the frozen medication bags, thaw the bags at room temperature or in the refrigerator before using. Make sure all the ice crystals have melted. If you have questions regarding the use of this medication, consult your doctor or pharmacist.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals as directed.
Continue to take aztreonam until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens.