Thursday, July 25, 2013

Cefepime Injection

It is a semi synthetic, broad spectrum, fourth generation cephalosporin. It exerts its effects by inhibiting the peptidoglycan synthesis in microbial cell wall.
Composition :250mg,500mg,1gm,2 gm
Indications :Moderate to severe pneumonia, septicaemia, UTI, skin & skin structure infections, intra-abdominal infections.
Contraindications :Impaired hepatic function. Impaired hypertension, hypersensitivity.
Safety Profile :Pregnancy, lactation, pediatric dose adjustment required.
Drug Interactions :Aminoglycoside & other antibiotic may increase the nephrotoxicity & ototoxicity.
Dosage :Febrile neutropenia thrice a day 1-2 gm IV, other 1-2 gm IV.



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