Thursday, July 25, 2013

Acyclovir Injection

Category: Antiviral
Acyclovir : It is deoxiguanosine analog and requires a virus specific enzyme for conversion to the active metabolite that inhibits DNA synthesis and viral replication.
Composition :250mg & 500mg
Indication :Genital Herpes Simplex, Mucocutaneous H Simplex Encephalitis, H Simplex Keratitis, Herpes Zoster, Chicken Pox etc.
Dosage :Adults: Herpes Simplex: 200 mg 5 times daily at 4 hrs interval for 5 days Herpes Zoster: 800 mg 5 times daily 4 hrs interval for 7 days Prophylaxis in Suppression: 200 mg 4 times daily
Children :(Abpve 2 yrs) Dose same as adult.
Children :(Below 2 yrs) Herpes Simplex: 100 mg 5 times at 4 hrs interval Prophylaxis: 100 mg 4 times daily at 6 hrs interval.
Contra-Indications :Hypersensitivity, glaucoma, psychiatric diseases, depression etc.
Special Precautions :Renal impairment necessitates dose reduction. Maintain adequate hydration






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